Achieving a Negative Fluid Balance

exp date isn't null, but text field is


Volume overload is very common in the later stages of critical illness, and achieving a negative fluid balance is key to helping patients liberate from mechanical ventilation and ultimately recover. I outline strategies for minimizing ins (avoid MIVF, use high concentration drips, switch IV to PO) and maximizing outs (stepwise diuresis with loop diuretics, thiazides, spironolactone, and acetazolamide). I also discuss special circumstances including cirrhosis, nephrotic syndrome, and hypoalbuminemia.

Author(s): Nick Mark, MD

Internal URL:


Attribution:   Title: “Achieving a Negative Fluid Balance”   Creator: “Nick Mark MD“  Source:OnePager ICU“   License: “CC BY-SA 3.0

Citation Example:   OnePagers: Mark NM, “Achieving a Negative Fluid Balance” Published 2020-10-23, OnePagerICU, URL: (accessed Date)