The Multiple Organ Dysfunction Score (MODS)

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Organ System Score Points
  0 1 2 3 4
Respiratory (PaO2/FiO2) > 300 226-300 151-225 76-150 ≤ 75
Renal (Serum Creatinine)
(μmol/l)		 ≤ 100 101-200 201-350 351-500 >500
Hepatic (Serum Bilirubin)
(μmol/l)		 ≤ 20 21-60 61-120 121-240 >240
Cardiovascular (PAR)
(HR x CVP/MAD)		 ≤ 10.0 10.1-15.0 15.1-20.0 20.1-30.0 > 30
Hematologic (Platelet Count)
(ml x 103)		 >120 81-120 51-80 21-50 ≤ 20
Neurologic 
(Glasgow Coma Scale)		 15 13-14 10-12 7-9 ≤ 6

The pressure-adjusted heart rate (PAR) is calculated as the product of heart rate (HR) multiplied by the ratio of the central venous pressure (CVP) to the mean arterial pressure (MAD).  The Glasgow Coma Scale is preferably calculated by the patient's nurse and is scored conservatively (for a patient receiving sedation or muscle relaxants, normal function is assumed, unless there is evidence of intrinsically altered mentation).  

(From: Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome.  Crit Care Med 1995; 23(10): 1638-52)

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  1. Title: The Multiple Organ Dysfunction Score (MODS)
  2. Author:  Michigan Medicine
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The Multiple Organ Dysfunction Score (MODS),  Michigan Medicine, Dept of Surgery ,  “CC BY-NC 4.0”

Last reviewed: 09 June 2021